Under the Sending Mail section, you should see the return address you will be using if you entered one under getting started.

The default domain should be blank, unless you were told to specify it by your ISP.

The SMTP server should be the same as your OUTGOING mail server the ISP told you to use.

Under Connection, there are three options you can choose. In most cases all three should be checked.

Under Message, there are three more options you can choose. As they are optional, you can choose which you would like, or none at all.

That's it... We're setup. Clcik OK at the
bottom and you should be able to send
and receive your mail! 
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